Yuanhong Li
2012
Abstract
Objective To investigate the effect of topical resveratrol on skin erythema induced by solar simulator ultraviolet irradiation.Methods Twenty volunteers were recruited and 6 experimental sites were separately marked on their bilateral backs.Sites 1 to 4 were topically applied with resveratrol combination with antioxidant,antioxidant,resveratrol,base,respectively.The products were applied to left-side followed by irradiation,and the products were applied to right-side after irradiation.Sites 5 and site 6 were separatedly designated as positive control and negative control sites.The irradiation last 4 days and skin erythema was observed.Results On the 1st and 2nd days after irradiation,no or only slight erythema were observed on site 1 to site 3.On the 3rd and 4th days,the erythema of site 1 and site 3 remained unchanged comparing to that on the 2nd day,whereas the erythema of site 2 became obvious than before and lighter than that of site 5.The erythema on left-side is slighter than that on right-side.Conclusion Topical resveratol could effectively prevent(more obviously) and reverse the skin erythema induced by solar simulator ultraviolet irradiation.