Putthong C, Panmanee T, Charoensit P, Ross S, Tongpoolsomjit K, Viyoch J.

Nutrients · 2024

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Abstract

Background/objectives UV radiation is a primary cause of skin damage and photoaging. β-carotene, a potent antioxidant, aids in mitigating UV-induced oxidative stress and enhancing skin photoprotection. This research aimed to evaluate the efficacy of a nutraceutical product designed to prevent photoaging. Methods The product consists of a blend of hemp seed oil and banana ( Musa AA), formulated as a chewable tablet. Healthy male participants aged 35-50 years were enrolled in a randomized, parallel, single-blind, placebo-controlled clinical trial. Participants received either the chewable nutraceutical (five tablets after meals in the morning and evening, equivalent to 8 ± 2 mg/day of β-carotene and 400 mg/day of PUFA) or a chewable placebo for 16 weeks. A total of thirty-six participants successfully completed the entire 16-week study. Results Administration of the nutraceutical resulted in a significant reduction ( p p p Conclusions The results indicate that the developed nutraceutical may offer effective protection against erythema, making it a promising option for preventing photoaging.